It’s been six years since ‘s beloved talk show went off the air — and now, she’s reflecting on what it taught her.
In an interview with PEOPLE and Entertainment Weekly‘s Editorial Director for the latest edition of , excerpted in this week’s issue of PEOPLE, the TV queen — and star of HBO’s upcoming — opens up about life after .
During the interview at , Winfrey, 63, admits that it wasn’t easy to adjust to life without the show, which ran for 25 seasons from 1986 to 2011 and remains one of the highest-rated talk shows in American television history.
“For about two years, I was off balance,” says Winfrey. “I was so accustomed to having an itinerary done for me and that itinerary just being jammed from the time I got up in the morning. I wouldn’t even look at it until was I done with the day. I’d just say, ‘Where am I next? What do we do now?’ ”
- Watch the full episode of , streaming now on People/Entertainment Weekly Network (PEN). Go to , or download the app for Apple TV, Roku, Amazon Fire TV, Xumo, Chromecast, Xfinity, iOS and Android devices. And for more on Oprah and Henrietta Lacks, pick up this week’s issue of PEOPLE, on newsstands Friday.
Despite the challenges of adjusting to her new life, Winfrey says she was “never depressed” after the show ended.
“I was just like, ‘Oh, okay. It’s 7:30, and I woke up when I heard the birds,’ ” she says. “I had to figure out how to set a schedule based on what I want to do. I don’t have to be in the office at any certain time. I don’t have a 9:00 show and a 1:00 show and then a 3:00 meeting afterwards.”
“How do I now kind of create a life based on what I want?” she continues. “I didn’t know what I wanted, so it took me a while to figure that out.”
The Immortal Life of Henrietta Lacks premieres April 22 at 8 p.m. ET on HBO.